Cold-adapted variants of influenza virus A
Identifieur interne : 002A75 ( Main/Exploration ); précédent : 002A74; suivant : 002A76Cold-adapted variants of influenza virus A
Auteurs : S. B. Spring [États-Unis] ; H. F. Maassab [États-Unis] ; A. P. Kendal [États-Unis] ; B. R. Murphy [États-Unis] ; R. M. Chanock [États-Unis]Source :
- Virology [ 0042-6822 ] ; 1977.
English descriptors
- Teeft :
- Academic press, Assay, Attenuated, Beare, Biological characterization, Certain pairs, Chanock, Chick kidney tissue culture, Cold adaptation, Cold variants, Complementation, Complementation group, Complementation groups, Embryonated eggs, Fowl plaque virus, Genetic properties, Hong kong, Immunobiological standards, Influenza, Influenza vaccine, Influenza vaccines, Influenza virus, Influenza viruses, International symposium, Lesion, Maassab, Measles virus, Monolayers, Mutant, Mutant pairs, Permissive temperature, Plaque, Plaque formation, Plaque titer, Poisson distribution, Recombinant, Restrictive temperature, Restrictive temperatures, Serial dilutions, Shutoff temperature, Surface antigens, Symposium series, Tissue culture, Vaccine, Vaccine strains, Variable interaction, Variant, Virology, Virus.
Abstract
Abstract: The genetic properties of seven cold-adapted variants of influenza virus A were compared with those of nine 5-fluorouracil (5-FU)-induced ts mutants. The 5-FU mutants had previously been placed into seven complementation-recombination groups; five of the seven cold-adapted variants also had the ts phenotype, and all five were shown to share the group 1 lesion. Three of the cold variants also had additional ts lesions.
Url:
DOI: 10.1016/0042-6822(77)90430-5
Affiliations:
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Le document en format XML
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<front><div type="abstract" xml:lang="en">Abstract: The genetic properties of seven cold-adapted variants of influenza virus A were compared with those of nine 5-fluorouracil (5-FU)-induced ts mutants. The 5-FU mutants had previously been placed into seven complementation-recombination groups; five of the seven cold-adapted variants also had the ts phenotype, and all five were shown to share the group 1 lesion. Three of the cold variants also had additional ts lesions.</div>
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